Database.use.hdl: https://cris.mruni.eu/cris/handle/007/21053
Now showing 1 - 10 of 20
  • research article
    Agyekum, Martin Wiredu
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    Nyieku, Florence Esi
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    Yeboah, Sylvia Boamah
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    Frempong-Ainguah, Faustina
    BMC research notes., p. 1-9.
    The burden of children’s disease in many low-and middle-income countries is associated with poor sanitation, including unsafe disposal of children’s stool. Infants and toddler stools pose a greater public health risk than adults. Studies on stool disposal in Sub-Saharan Africa (SSA) and Ghana have focused on prevalence, patterns, and associated factors. Nevertheless, these studies have not focused on factors that independently influence rural and/or urban child stool disposal. This study, therefore, examines factors associated with safe child stool disposal in rural areas separately from urban areas towards Ghana’s readiness for ending open defaecation by 2030.
      1WOS© IF 1.8WOS© AIF 1.8Scopus© SNIP 0.869
  • research article;
    Canario, Rita
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    Peccatori, Fedro Alessandro
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    Dierickx, Kris
    Cancers. [Basel] : MDPI AG, 2022, vol. 14, iss. 17, ARTN 4325., p. 1-21
    (1) Background: Current scientific evidence suggests that most cancers, including breast cancer, can be treated during pregnancy without compromising maternal and fetal outcomes. This, however, raises questions regarding the ethical implications of clinical care. (2) Methods: Using a systematic literature search, 32 clinical practice guidelines for cancer treatment during pregnancy published between 2002 and 2021 were selected for analysis and 25 of them mentioned or made references to medical ethics when offering clinical management guidance for clinicians. (3) Results: Four bioethical themes were identified: respect for patient’s autonomy, balanced approach to maternal and fetal beneficence, protection of the vulnerable and justice in resource allocation. Most guidelines recommended informing the pregnant patient about available evidence-based treatment options, offering counselling and support in the process of decision making. The relational aspect of a pregnant patient’s autonomy was also recognized and endorsed in a significant number of available guidelines. (4) Conclusions: Recognition and support of a patient’s autonomy and its relational aspects should remain an integral part of future clinical practice guidelines. Nevertheless, a more structured approach is needed when addressing existing and potential ethical issues in clinical practice guidelines for cancer treatment during pregnancy.
      2WOS© IF 5.2WOS© AIF 5.7Scopus© SNIP 1.086
  • research article
    Beiša, Augustas
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    Kvietkauskas, Mindaugas
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    Beiša, Virgilijus
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    Stoškus, Mindaugas
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    Ostanevičiūtė, Elvyra
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    Griškevičius, Laimonas
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    Šeinin, Dmitrij
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    Šileikytė, Auksė
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    Strupas, Kęstutis
    Experimental and clinical endocrinology & diabetes. Stuttgart : Johann Ambrosius Barth Verlag, 2019, vol. 127, iss. 4., p. 247-254
    BACKGROUND: Ultrasound guided fine needle aspiration biopsy with cytologic analysis is an initial step in diagnostic of thyroid nodules. Unfortunately, up to 30% of biopsies are indeterminate and diagnostic surgery is required. The aim of this study was to estimate the diagnostic value of BRAF V600E mutation status combined with cytomorphological features for diagnosis of papillary thyroid cancer (PTC) in cytologically indeterminate thyroid nodules. METHODS: A prospective study analyzed patients who had ultrasound suspicious thyroid nodules, underwent fine needle aspiration and cytological examination, and were classified according to the Bethesda system. Patients from indeterminate diagnostic categories were examined for BRAF V600E mutation and 22 cytomorphological features, and underwent thyroid surgery. A binary logistic regression model was used to evaluate the diagnostic utility. RESULTS: A total of 219 patients met study criteria. After histological examination, 77 (35.2%) patients were diagnosed with PTC and 142 (64.8%) with benign nodular thyroid disease. According to logistic regression model, significant features for PTC diagnosis were: liquid colloid consistency, papillary structures, eosinophilic colloid bodies, and BRAF V600E mutation. Risk groups classified by this model have sensitivity of 80.5% (95% CI: 69.9 to 88.7), specificity of 99.3% (95% CI: 96.1 to 100), positive predictive value of 98.4% (95% CI: 89.8 to 99.8), negative predictive value of 90.4% (95% CI: 85.7 to 93.7), and accuracy of 92.7% (95% CI: 88.4 to 95.8) for PTC diagnosis. CONCLUSIONS: Evaluation of BRAF V600E mutation status combined with cytomorphological features for diagnosis of PTC in cytologically indeterminate thyroid nodules can significantly improve diagnostic accuracy and reduce the number of diagnostic operations (calculator available at www.ptc-calc.we2host.lt).
    WOS© IF 2.058WOS© AIF 4.315Scopus© SNIP 0.608
  • research article;
    Drungilas, Darius
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    Voznak, Miroslav
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    Kurmis, Mindaugas
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    Jakovlev, Sergej
    The scientific world journal. New York : Hindawi Publishing Corporation, 2015, vol. 2015, art. no. 569841., p. 1-6
    Usually, a hydrometeorological information system is faced with great data flows, but the data levels are often excessive, depending on the observed region of the water. The paper presents advanced buoy communication technologies based on multiagent interaction and data exchange between several monitoring system nodes. The proposed management of buoy communication is based on a clustering algorithm, which enables the performance of the hydrometeorological information system to be enhanced. The experiment is based on the design and analysis of the inexpensive but reliable Baltic Sea autonomous monitoring network (buoys), which would be able to continuously monitor and collect temperature, waviness, and other required data.The proposed approach of multiagent based buoy communication enables all the data from the costal-based station to be monitored with limited transition speed by setting different tasks for the agent-based buoy system according to the clustering information.
    Scopus© SNIP 0.743
  • research article
    Yajima, Daisuke
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    Ishihara, Kenji
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    Takeichi, Hisako
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    Raudys, Romas
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    Biržinienė, Vilija
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    Saito, Hisako
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    Hayakawa, Mutsumi
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    Sakuma, Ayaka
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    Inokuchi, Go
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    Makino, Yosuke
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    Motomura, Ayumi
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    Chiba, Fumiko
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    Torimitsu, Suguru
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    Ishii, Namiko
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    Iwase, Hirotaro
    Chiba medical journal. Chiba : Chiba Univeristy, School of Medicine, 2014, vol. 90, no. 4., p. 123-130
    The practice of forensic medical examination of living persons is to record their injury characteristics, identify mechanism of injury, estimate time of injury, determine degree of severity, and to collect samples in sexual violence cases. While this practice is uncommon for forensic pathologists in Japan, it is a major part of forensic work in Europe. Forensic pathologists produce documents for many purposes: official evidence in judicial procedures, requests for workers􀊟 compensation and accidental insurance, and deterrence against future violence. In 2012, Lithuanian forensic pathologists dealt with 19,933 cases. Examination of injury accounted for 98􀋋 of all cases. The other 2􀋋 related to sexual crime. Certified forensic experts determine degrees of severity of injury according to the rules established by agreement of the related Lithuanian governmental ministries. In Japan, by contrast, this practice is unregulated and clinical doctors usually perform forensic examinations. Depending on the doctor, the estimated degree of injury can vary. Producing documentation or testifying in court can also be a burden for clinical doctors. Forensic medical examination of living persons will become more important in Japan in future because of an increase in child abuse cases and the need to produce legally acceptable scientific evidence.
      4Scopus© SNIP 0
  • research article
    Juška, Alfonsas
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    Trace elements and electrolytes. Oberhachin : Dustri-Verlag, 2013, vol. 30, no. 4., p. 167-172
    Aim of this research was to investigate the functioning of chloride/bicarbonate exchanger in thymic lymphocytes in view of better understanding the mechanisms involved in chloride fluxes. Materials and methods: Experiments were performed using a suspension of freshly isolated thymocytes representing a homogeneous population of thymic lymphocytes. Thymic lymphocytes were isolated from Wistar male rats’ gl. thymus, 6 – 7 weeks of age. The cells were incubated with the MQAE chloride dye. Cl– concentration in the cytoplasm of lymphocytes was measured spectrophotometrically. A model of exchanger activation has been suggested based on the analysis of experimental data. Results and conclusion: It has been shown that: (a) involvement and activity of chloride transport mechanisms depend on where chloride concentration is made zero: in the medium or cytoplasm; (b) under certain experimental conditions, the activity of the exchanger proceeds in two steps: switching on and off; (c) in the absence of HCO3–, the relative rates of the exchanger transitions decline considerably, its efficacy remaining the same. Chloride/bicarbonate exchanger merits further research under conditions closer to physiological.
    WOS© IF 0.452WOS© AIF 4.204Scopus© SNIP 0.417
  • research article;
    Dapšys, Kastytis
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    Mačiulis, Valentinas
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    Arnfred, Sidse M.
    Psychiatry research: neuroimaging. Shannon : Elsevier Ireland Ltd, 2013, vol. 211, no 2., p. 183-185
    The 40-Hz auditory steady-state responses (ASSRs) of 14 medicated schizophrenic patients were recorded in eyes-open and eyes-closed conditions as previously done in healthy volunteers. Patients show significantly increased precision of the evoked response with eyes closed, and a significant increase of broad-band noise activity when eyes are open.
    WOS© IF 2.831WOS© AIF 3.752Scopus© SNIP 1.025
  • research article;
    Grikinienė, Jurgita
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    Meilus, Vaidevutis
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    Didžiapetrienė, Janina
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    Matusevičius, Paulius
    Trace elements and electrolytes. Oberhachin : Dustri-Verlag Dr. Karl Feistle, 2012, vol. 29, no. 4., p. 256-261
    Conclusion: The understanding of the hypothesized NaVP mechanism may lead to the recognition of Cl– as an important mediator in tumor development and as a novel therapeutic target for cancer.
    WOS© IF 0.5WOS© AIF 4.121Scopus© SNIP 0.304
  • conference poster;
    Šinkariova, Liuda
    Psychology and health, p. 152-152
    Despite many theories and scientist working at children’s mental health, it is still getting worse every year. This current hypothesis is that there are other factors that influence child‘s emotional and behavioral problems (EBP). There is some evidence that one of these factors could be exposure to environmental pollutants. The main research question was what are the main factors of environment pollution which influence child’s EBP. The aim of this paper is to highlight the main environment pollution factors influencing children EBP. Methods:Papers published from 2002 onwards were revied with regard to scientific context. Findings:The main environment pollution factors, influencing child’s EPB, are heavy metals, air pollution, noice and prenatal ETS exposure. Discussion:There are many preventive programs regarding social and psychological child’s environment. This paper suggests that public health policies have to be pointed to systematical programs regulating environment pollution impact on child’s mental health.
      1WOS© IF 1.95WOS© AIF 1.799Scopus© SNIP 1.187
  • research article;
    Driziene, Z.
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    Uleckienė, Saulė
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    Kazbarienė, Birutė
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    Didžiapetrienė, Janina
    Trace elements and electrolytes. Deisenhofen-Munich : Dustri-Verlag, 2011, Vol. 28, no. 4., p. 208-212
    Aim and methods. Hypomagnesemia is a frequent adverse effect of chemotherapy in cancer patients. Its gender-dependent peculiarities are unknown. The aim of the current work was to define peculiarities of urinary magnesium (Mg) excretion in healthy adolescents; to elucidate gender-related differences in Mg urinary excretion; to determine a correlation between urinary Mg excretion and arterial blood pressure (BP) in healthy adolescents. Mg was examined in diurnal and nocturnal urine of adolescent boys (n = 27) and girls (n = 42) aged 13 - 17 years. Urinary Mg (both during day and night) was monitored 24-h concomitantly with BP (hourly) in 44 adolescents (22 girls and 22 boys). Additionally, of the same girls 15 were examined during different phases of their menstrual cycle (follicular, ovulation and luteal). Results. 24-h urinary Mg excretion was significantly higher in boys than in girls (2.66 +/- 0.9 mmol vs. 2.1 +/- 0.9 mmol; p < 0.05). Nocturnal systolic BP was significantl y higher (p < 0.05) in boys than in girls in all phases of their menstrual cycle. Diurnal systolic BP in boys was significantly higher than in girls during the follicular phase. It revealed a significant positive correlation between Mg excretion and BP in boys at night (p < 0.05). Girls exhibited a significant inverse correlation between Mg nocturnal excretion and BP (p < 0.05) during the luteal phase of their menstrual cycle, as well as a significant negative correlation between diurnal Mg excretion and BP (p < 0.05) during the ovulation phase. Urine Mg was negatively related to height in girls (p < 0.05). Conclusion. Mg urinary excretion is related to gender, height, circadian rhythm, and blood pressure. The further preclinical and clinical studies of gender-related risks of hypomagnesemia under chemotherapeutic treatment could contribute to improving the efficacy of anticancer treatment.
    WOS© IF 0.469WOS© AIF 4.112Scopus© SNIP 0.264